The NIH's recently implemented Data Management and Sharing (DMS) Policy, effective January 25, 2023, mandates that all research supported by NIH funding must develop a data management and sharing plan. The ImmunoX Office of Collaborative Research (OCR) is committed to supporting the data management and sharing needs of its members and is introducing a Data Management & Sharing RFA to assist ImmunoX researchers in planning and implementing these requirements, including creating DMS plans that align with sponsor expectations. As such, the primary objective of this RFA is to ensure the long-term, high-quality curation, storage, and accessibility of research data while adhering to the new NIH guidelines and policies for the UCSF community.