Neurocore-iMMM 

Round 1

iMMM use (i.e. observational or interventional)

iMMM-derived definitions of secondary brain injuries 

iMMM use according to recognized guidelines (e.g., Seattle International Severe Traumatic Brain Injury Consensus Conference)

iMMM-related imaging protocol (e.g., routine postplacement imaging)

pre-operative reversal (e.g., anticoagulant)

pre-operative prophylaxis drug treatment (e.g., antibiotics, anti-epileptic drugs)

iMMM recording protocol (e.g. expected duration, end of monitoring indication)

suspicion of iMMM-related infection documentation protocol (e.g., the systematic culture of withdrawn material)

placement settings (e.g., OR vs. bedside)

iMMM targeting strategy* (e.g., right hemisphere, least-injured hemisphere)

procedure details (e.g., duration, craniotomy dimension)

device used for implantation accuracy (e.g., neuronavigation)

type of probes used (e.g., PbtO2, microdialysis, etc.)

tech specs of fixation device (e.g., number of lumen, MRI-compatibility, etc.)

tech specs of iMMM data recording systems

iMMM time recording (i.e. continuous or punctual) for each modality

iMMM bedside presentation for neurocritical caregivers

manufacturer's details (e.g., models identifiers)

device regulatory details (e.g., CE/FDA-approval)

time-specific monitoring patterns related to presumed pathophysiological changes

surgeon's expertise (e.g., seniority, experience with iMMM)

probe repeated insertions (i.e., intraoperative or secondary repositioning of iMMM)

only significant ones (i.e., causing change of management)

breaking (of probes and/or fixation method)

prospective registry for iMMM-related studies

prospective registry for iMMM individual cases

guidelines/documentation to implement iMMM