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(3)EACCME® participant's evaluation form
Liver transplantation in acute liver failure caused by metabolic diseases: indications and contraindications
Below you will find several questions about the contents and other aspects of the webinar. Once the webinar ends, you have
up to 2 weeks
to submit your answers and get ECMEC®s accreditation certificate.
Please enter your full name as it appears on the registration form:
*
QUESTIONS
1) A 12-year-old child presents with acute liver failure, Coombs-negative hemolytic anemia, rapidly increasing bilirubin, INR 3.1, acute kidney injury, low alkaline phosphatase relative to bilirubin, and grade II encephalopathy. Wilson disease is suspected, but ATP7B testing is still pending. What is the most appropriate management strategy?
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A
Wait for genetic confirmation before contacting the transplant centre
B
Start chelation therapy and reassess transplant need after several weeks
C
Treat with corticosteroids because autoimmune hepatitis cannot be fully excluded
D
Urgently refer/list for liver transplantation while starting medical therapy and considering plasma exchange as a bridge
E
Avoid liver transplantation because neurological involvement in Wilson disease is an absolute contraindication
2) Which situation is generally considered a contraindication to liver transplantation in mitochondrial hepatopathy?
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A
Liver-limited disease without neurological involvement
B
Progressive liver failure with preserved cardiac and neurological function
C
Acute liver failure in a potentially transplant-correctable metabolic defect
D
Alpers/POLG-related disease with severe neurological involvement and refractory seizures
E
Isolated coagulopathy in a clinically stable child
3) In severe hyperammonemia due to a suspected urea cycle disorder, what is the most appropriate initial approach?
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A
Immediate liver transplantation as the first detoxification method
B
Observation until encephalopathy develops
C
Emergency metabolic stabilization, ammonia-lowering therapy, and dialysis when indicated
D
High-dose copper chelation therapy
E
Avoiding renal replacement therapy because it worsens liver failure
4) Quality of the event
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5) Relevance of the event
Did the event fulfil your educational goals and expected learning outcomes?
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Was the presented information well balanced and consistently supported by a valid scientific evidence base?
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6) Suitability of formats used during the event
Was there adequate time available for discussions, questions & answers and learner engagement?
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7) Ways the event affects clinical practice
Will the information your learnt be implemented in your practice?
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Can you provide ONE example how this event will influence your future practice?
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8) Commercial bias
Did all the speakers provide their potential conflict of interest declaration with the sponsor(s) as a second slide of their presentations?
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No
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Can you provide an example of biased presentation in this activity?
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Do you agree that the information was overall free of commercial and other bias?
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Thank you very much for your time!
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